The Brain Penetrant CDK4/6 Inhibitor, PRT3645, is Highly Effective in Combination with Targeted Therapies in Preclinical Models of NSCLC, CRC and HER2-positive Breast Cancer

 Yue Zou, Srijita Dhar, Kirsten Gallagher, Andrew Buesking, Sarah Pawley, Ryan Holmes, Xiaowei Wu, Katarina Rohlfing, Min Wang, Joseph Rager, Tom Emm, Stefan Ruepp, Miles Cowart, Jing Ni, Jean Zhao, Bruce Ruggeri, Andrew Combs, Kris Vaddi, Sandy Geeganage, Ashish Juvekar, Sang Hyun Lee, Peggy Scherle