Deborah Morosini, M.D., M.S.W.


Executive Vice President and Chief of Clinical Affairs

Deborah Morosini, M.D., M.S.W. joined Prelude Therapeutics in 2020 and currently serves as Executive Vice President and Chief of Clinical Affairs. She brings to Prelude extensive expertise in oncology drug development, clinical genomics, and philanthropic activism. She previously served as Vice President of Clinical Affairs and Patient Engagement (Chief Patient Officer) at Loxo Oncology, where she built and led patient engagement and enrollment strategy, medical affairs, and patient advocacy. Dr. Morosini played a key role in the launch of Vitrakvi® (larotrectinib) via a co-promote partnership with Bayer, and conducted launch preparations for LOXO-292, a RET inhibitor for lung and thyroid cancer. Prior to Loxo, she was an early team member at Foundation Medicine, where she developed a niche specialty in the genomics of adolescent and young adult cancer. Before joining Foundation Medicine, she founded and led the molecular pathology group at AstraZeneca Pharmaceuticals, where she helped develop and implement biomarker strategies for biomarker-driven trials. Prior to AstraZeneca, Dr. Morosini served as Director of Pathology for Ardais, a clinical genomics biotechnology company. She has been featured as a spokesperson for numerous non-profit and government events in oncology and has provided expert commentary for national broadcast media. She has served on numerous national oncology non-profit boards, and currently serves on the Board of Directors for ClinWiki and the SAB for Target Cancer and Upstage Lung Cancer. Dr. Morosini earned her B.A. in English from Mount Holyoke College, her M.S.W. from NYU Graduate School of Social Work, and her M.D. from Boston University School of Medicine. She completed a pathology residency at Boston Medical Center.